JAMA: Long-Term Exposure To Cannabis Smoke Not Associated With Adverse Effects On Pulmonary Function

JAMA: Long-Term Exposure To Cannabis Smoke Not Associated With Adverse Effects On Pulmonary Function: ""Our findings suggest that occasional use of marijuana ... may not be associated with adverse consequences on pulmonary function."

San Francisco, CA: Exposure to moderate levels of cannabis smoke, even over the long-term, is not associated with adverse effects on pulmonary function, according to clinical trial data published Tuesday in the Journal of the American Medical Association (JAMA).

Investigators at the University of California, San Francisco analyzed the association between marijuana exposure and pulmonary function over a 20-year period in a cohort of 5,115 men and women in four US cities.

Predictably, researchers "confirmed the expected reductions in FEV1 (forced expiratory volume in the first second of expiration) and FVC (forced vital capacity)" in tobacco smokers. By contrast, "Marijuana use was associated with higher FEV1 and FVC at the low levels of exposure typical for most marijuana users. With up to 7 joint-years of lifetime exposure (e.g., 1 joint/d for 7 years or 1 joint/wk for 49 years), we found no evidence that increasing exposure to marijuana adversely affects pulmonary function.""

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